- New California Rangers wear modified LAPD riot armor. The trenchcoat guy from the teaser is identified as one in the article.
- Gun modifications will increase damage, ammo capacity, accuracy, rate of fire and more
- The player will be able to have two or three companions in their party
- Unsurprisingly, deathclaws and radscorpions are mentioned
- The dinosaur casino is identified as Dinky the Dinosaur
- NCR is described as large and powerful but bureaucratic.
- J.E. Sawyer: "The Karma system is mostly the same as in Fallout 3, but checked less often. Mostly we rely on reputation, because that's what people know. Karma is just a general indicator of how much of a sonofabitch you are. If you murder people in secret, your reputation doesn't go down because no on knows you did anything, so you can maintain a good reputation but your karma has tanked really heavily. Karma does influence some things, but reputation is usually what most people in the world base their opinions of you on."

You'll also use a vitomatic vigor tester machine to determine your S.P.E.C.I.A.L stats. In a way that is similar to seeing a therapist, the doc gives you a personality test to determine your skills and define your character. He'll ask you questions like what comes to mind when you hear the word "dog" or "light," and the responses you give can be straightforward or slightly disturbing. For example, a couple of the optional responses for hearing the word "mother" included things like "cookie jar" and "human shield."

Those who pick up the game through Wal-Mart or Steam get the Caravan Pack, offering lightweight leather armor, a sturdy caravan shotgun, four repair kits, and a pair of binoculars.